BPC-157 / TB-500 after labral repair, worth starting early

BPC-157 / TB-500 after labral repair, worth starting early?

Thread summary

The labral tissue is fibrocartilage, not tendon, so the healing biology is a different animal than what BPC-157 gets studied for. (shared by @LabRatLouis)
Didn't do labrum but I started TB-500 about day 10 post-op on my elbow repair once the incision was closed and dry. (shared by @tendon_tinker)
Agree with that. (shared by @Dr_Rehab_Ray)
Early post op for a labral repair the surgeon's protocol is driving 90 percent of the outcome, sling time, PT phases, capsule protection. (shared by @CoachTerrell)

Top answer from @LabRatLouis. Jump to reply

Had my supraspinatus repair done back in Jan but my surgeon mentioned my labrum was also fraying a bit and might need a separate look down the road. Been reading up in case that happens. Anyone actually run BPC-157 or TB-500 after a labral repair specifically? Curious when you started post-op, how you dosed around the sling phase, and whether it actually changed your healing timeline or just made you feel like you were doing something. Not trying to shortcut PT, just want real data points from people who've been through it.

Two years of patience beat six months of panic.

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tendon_tinkerAustin, TX6 points18d ago

Didn't do labrum but I started TB-500 about day 10 post-op on my elbow repair once the incision was closed and dry. Tracked ROM weekly in a spreadsheet, honestly hard to separate it from just normal healing curve. My numbers looked slightly ahead of where my surgeon's typical timeline chart said I'd be at week 6 but that's an n of 1 against a chart, not a control group.

Measure it or it did not happen.

jumpers_knee_jessOmaha, NE8 points18d ago

Following, my shoulder guy on the team is staring down the same surgery.

Isometrics before ice. Every time.

LabRatLouis Top answerBoston, MA9 points18d ago

The labral tissue is fibrocartilage, not tendon, so the healing biology is a different animal than what BPC-157 gets studied for. Doesn't mean it can't help the surrounding capsule and soft tissue, but be careful assuming the same mechanism applies to the labrum itself.

Preclinical is not a promise.

AchillesAnnaPortland, OR3 points18d ago

Not a shoulder case but I'll say the early post-op window is where I've seen peptides get the most credit and the least evidence. Healing is just fast early on regardless.

Slow is smooth. Smooth is 5k pace eventually.

CoachTerrellAtlanta, GA6 points18d ago

Early post op for a labral repair the surgeon's protocol is driving 90 percent of the outcome, sling time, PT phases, capsule protection. Peptides are a side conversation at that stage, not the main event.

You cannot inject your way out of a bad program.

Dr_Rehab_RayCleveland, OH6 points18d ago

Agree with that. Labral repairs are very protocol dependent on the surgeon's exact technique and tear location, so whatever you run, don't let it tempt you to push range or load ahead of where your surgeon has you cleared. The graft doesn't care what's in the syringe if you load it too soon.

Load is the drug with the best data.

slow_healer_samBoise, ID2 points18d ago

How many weeks in before you'd even expect to notice a difference either way

Still here. Still slow.

rotator_cuff_rickOPNaperville, IL6 points18d ago

Appreciate the input. Sounds like it's more of a maybe-helps-the-margins thing than a game changer. Guess I'll just do the boring protocol work and see where the labrum discussion goes if surgery happens.

Two years of patience beat six months of panic.